Immunoglobulin & Antibody-Class Kit Catalog
Immunoglobulin Class Coverage by Species
The table below summarizes which immunoglobulin classes and subclasses are represented by dedicated kits for each species currently in this catalog. A dash indicates no dedicated class-specific kit is listed for that species in this collection.
| Species | IgG / Subclass | IgA | IgM | IgE | Notes |
|---|---|---|---|---|---|
| Mouse | IgG2b (E-90G2B) | — | — | — | Subclass-specific quantification kit |
| Human | — | — | IgM anti-HBc (KO31005096) | — | Antigen-specific IgM antibody detection, not total serum IgM quantification |
| Cat | — | — | — | — | No dedicated immunoglobulin-class kit currently listed |
| Rat | — | — | — | — | No dedicated immunoglobulin-class kit currently listed |
| Dog | — | — | — | — | No dedicated immunoglobulin-class kit currently listed |
Human hepatitis B antibody kits without a specified class (anti-HBs, total anti-HBc) detect pooled antibody response rather than a single immunoglobulin isotype and are listed for reference rather than as class-specific IgG/IgA/IgM/IgE measurements.
Why Immunoglobulin Class Quantification Matters
Research Relevance of Antibody Class Quantification
Immunoglobulins are not a single uniform pool of antibody; they are organized into distinct classes and, within IgG, further into subclasses that differ in effector function, half-life and tissue distribution. Measuring a specific class rather than total immunoglobulin gives researchers information that a bulk antibody titer cannot: an elevated IgM response typically signals a recent or primary exposure, while IgG predominance points to an established or memory response. IgG subclass ratios — such as the IgG2b target measured in the mouse kit in this collection — are used in model systems to characterize Th1/Th2-skewed immune responses, vaccine-induced immunity, and antibody-mediated effector mechanisms that vary by subclass.
In comparative and veterinary research, class-specific assays support studies of maternal antibody transfer, mucosal immunity (IgA), and allergic or parasitic disease models (IgE), where the relevant immunoglobulin class differs from the one most commonly measured in human diagnostic contexts. Antigen-specific class detection, such as the IgM-class anti-HBc assay included in this catalog, is also used clinically and in research to distinguish recent from past exposure, since IgM reactivity to a pathogen antigen typically declines as the response matures toward IgG.
Antibody deficiency and dysregulation research likewise depends on accurate class-level data, since a deficiency may be isolated to one immunoglobulin class while others remain normal — a pattern that total-antibody assays alone would not reveal. For a deeper walkthrough of how IgG, IgA, IgM and IgE assays are distinguished and applied, see Immunoglobulin Subclass ELISA Kits: IgG, IgA, IgM and IgE Explained. Researchers comparing findings across species may also find it useful to review the broader catalog organization in Veterinary & Animal ELISA Kits and Human ELISA Kits.