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Due to the positive results achieved by the INTENS consortium, the European Commission has decided to publish an article on INTENS, which has been included in the “Success stories” section of the EC website. In the article the latest results of the project are illustrated. The INTENS project focused on developing a strategy for autologous tissue engineering – or the process of treating an individual using their own cells or tissues. “The results we have achieved so far have surpassed all…

As many other research projects, the INTENS project has been heavily affected by the COVID-19 pandemic : hospitals and medical staff have been overwhelmed with the COVID-19 patients, while lockdown measures taken by governments sharply halted research activity. After different months, research centres have been able to reopen with massive restrictions: reduced number of staff members allowed accessing the centres, reduced time that researchers can spend in laboratory, facilities still closed or dedicated to COVID-19 projects/clinic-related practices only. Most people in…

We are delighted to report that in the last months we have achieved very important results. In particular, some significant research outcomes have been published in Nature  and Nature Medicine. The implication of these results is so relevant to the field that Nature Medicine decided to run an editorial on the topic. Also Nature Review Gastroenterology and Hepatology wrote an article on this topic. To summarise the most recent findings reported in these 2 papers: 1) We constructed autologous jejunal mucosal grafts using biomaterials…

On the 30th October 2019, one of INTENS researchers from UCL team, Giovanni Giobbe, participated in n-TRACK Open Day held at the Trinity Hall College (in Cambridge). This event was organised by partners from n-TRACK Project (an H2020 funded project). The aims of this workshop was to meet project partners, exchange views and learn about new technologies on nanomaterials in biomedical applications. Giovanni Giobbe gave a presentation on “Extracellular matrix hydrogel derived from decellularized tissues enables endodermal organoid culture”, as…

INTENS has been working with The Short Gut Families Support Group to hear and answer their questions about our research. The support group, which is a global network of support for anyone ‘who knows and loves a child with short gut syndrome or a similar diagnosis’ is run through Facebook and has over 3000 members. Being in dialogue with those affected by short gut syndrome is of the upmost importance to INTENS, in sharing insight and shaping future priorities for…

In a recent paper, researchers have shown that all immature cells that will become gut cells, can develop into stem cells. Partially funded by INTENS, the findings could help improve stem cell therapy. Stem cells are found throughout our bodies and play a lead role in repairing and renewing our tissues and organs. For example, stem cells in our gut make new gut lining cells to replenish old ones. Up to now, it was thought that whether or not an…

Enthusing families with stem cell biology at Cambridge Science Festival As part of the energetic “Cambridge UK Crew”, scientists from INTENS participated in the Cambridge Science Festival on the 24th March 2019 at the Cambridge Academy for Science and Technology.  The Cambridge Science Festival is a yearly event that spans two weeks, with engagement from local scientists, academia, and biotech companies to share with the public the most recent advances in science and technology.  The last day of this two-week…

On Saturday 23rd October, over 300 visitors enjoyed an array of fun and hands-on activities at the annual Family Fun Day at Great Ormond St Hospital. INTENS consortium organised activities explaining how to create organs in the lab, skilfully led by the researchers themselves, opening up the opportunity for dialogue about the work of the consortium and being a scientist. Among the different activities the visitors enjoyed, there were a virtual reality tool allowing ‘to see the organs inside their…

On Friday 28th September, INTENS partners met in London at The Francis Crick Institute to discuss progress and forge directions. The multi-disciplinary and highly collaborative project team presented scientific progress and used combined expertise to outline the next steps. During the richly productive meeting, INTENS partners also discussed the public engagement work of the consortium and had the opportunity to talk with the family of a patient affected by Short Bowel Syndrome, the condition that INTENS work is journeying towards…